Dr. Philipp Voigt, Assistant Professor Welcome Trust Centre for Cell Biology (WTCOB)
Dr. Philipp Voigt
Assistant Professor
Welcome Trust Centre for Cell Biology (WTCOB)
University of Edinburgh
Seminar Title: 鈥淗istone Methylation Crosstalk at Developmental Genes鈥�
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Host Lab: Lisa Munter
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Seminar:听听听听听听听听听听听听听听听听听听
Wednesday, August 2, 2017
12:00pm听
Room 1345
McIntyre Medical Sciences Building
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The genetic information听 of eukaryotic organisms is packaged into chromatin, a complex assembly of DNA, RNA, and proteins. The basic unit of chromatin is the nucleosome, which is formed by DNA wrapping around a histone octamer. Histones not only constitute the structural backbone of chromatin but also provide ample opportunity for regulating听 gene expression. They undergo a host听 of posttranslational modifications, which are thought to impact transcription either by directly modulating chromatin structure or by recruiting effector proteins. The overarching goal of research in our lab is to determine the mechanistic intricacies of histone modifications. Moreover, we aim to understand how different systems of chromatin modifiers interact to regulate and fine-tune gene expression.