/tropmed/aggregator J.D. MacLean Centre for Tropical & Geographic Medicine - aggregated feeds en https://pubmed.ncbi.nlm.nih.gov/42543082/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20260803010606&v=2.20.0.post5+40e1b98 CONCLUSIONS: This guideline offers a framework for treatment intensification beyond GLP‑1 RA monotherapy in T2DM, emphasizing shared decision‑making based on glycemic goals, hypoglycemia risk, weight needs, and patient preferences. Sun, 02 Aug 2026 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/42542126/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20260802005546&v=2.20.0.post5+40e1b98 BACKGROUND: Inadequate access to clinical bacteriology testing in low-resource settings compromises individual patient care and contributes to antimicrobial resistance. Funders, policy makers, and health administrators working to expand bacteriology testing in sub-Saharan Africa require evidence-based guidance. The aim of this study was to assemble a costed consensus list of minimum equipment and consumables required to implement and operate a functional clinical bacteriology laboratory in... Sat, 01 Aug 2026 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/42532030/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20260731004508&v=2.20.0.post5+40e1b98 Evolving genomic diversity of Mycobacterium tuberculosis complex pathogens is poorly known in French Polynesia, a remote archipelago in the southern Pacific Ocean. A total of 321 mycobacteria sampled from 321 patients presenting pulmonary tuberculosis between 1998 and 2010 at the microbiology laboratory of the French Polynesia Hospital Centre in Tahiti were whole genome sequenced (WGS), disclosing three major M. tuberculosis sensu stricto sublineages: L4.4.1.1 S-type, L4.1.1.3 X-Type, and... Thu, 30 Jul 2026 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/42517708/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20260729002410&v=2.20.0 AbstractAs part of a multi-year surveillance program of tick-borne diseases, we describe babesia surveillance of blood donors using nucleic acid tests conducted in 2025 and summarize cases of babesiosis reported by public health officials in Nova Scotia, Canada, from 2023 through 2025. Among 10,976 blood donor specimens, one specimen, collected from a blood donor in Nova Scotia Health's Western Zone, was positive, although this result was unable to be confirmed. Since babesiosis became... Tue, 28 Jul 2026 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/42405696/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20260707012540&v=2.20.0 No abstract Mon, 06 Jul 2026 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/42404989/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20260707012540&v=2.20.0 CONCLUSION: This study underscores the complex barriers health care providers face in delivering HCV care to immigrant populations in Canada. While some challenges reflect broader health care system gaps, they are compounded for immigrants by linguistic and cultural differences. Strengthening provider capacity, improving system coordination, and embedding culturally and linguistically responsive approaches are essential to advancing HCV elimination. Mon, 06 Jul 2026 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/42391310/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20260703003341&v=2.20.0 Dracunculiasis, or Guinea worm disease (GWD), was targeted for eradication in 1986 after which, the annual incidence decreased by over 99.9%. As human cases of GWD near elimination, dogs have become the primary reservoir for the parasite and remain a challenge for eradication efforts. The high burden of GWD in dogs relative to humans highlights the need for therapeutic interventions in conjunction with behavioral interventions. Laboratory experiments in ferrets demonstrated that flubendazole is... Thu, 02 Jul 2026 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/42338577/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20260625002421&v=2.20.0 INTRODUCTION: The gut microbiome influences cardiovascular health through metabolite production and immune modulation. Gut microbial dynamics and cardiovascular outcomes are also shaped by biological sex. However, sex-specific responses to myocardial infarction (MI) that involve the gut microbiome and intestinal milieu remain poorly defined, particularly in older hosts. Here, we characterize gut microbiome structure and function alongside physiological and immune responses to MI across multiple... Wed, 24 Jun 2026 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/42310812/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20260619001221&v=2.20.0 No abstract Thu, 18 Jun 2026 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/42276312/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20260613002857&v=2.20.0 CONCLUSIONS: The survey identified potential weaknesses in novel pathogen preparedness with respect to diagnostic capacity for OROV testing at specialized travel medicine clinics participating in two international networks. These findings provide an opportunity to implement measures to improve communication and planning and to strengthen diagnostic infrastructure prior to future outbreaks. Thu, 11 Jun 2026 06:00:00 -0400